This retrospective analysis of U.S. commercial claims data examined the clinical characteristics, healthcare resource utilization (HCRU), and costs of patients with PH. Authors Mucha L, Hoppe B, Silber A, Wang Z, Miyasato G, Skaar J, Langman C Journal Journal of Managed Care & Specialty Pharmacy; AMCP Nexus Virtual 2020 View publication…
Primary hyperoxalurias (PH; types 1, 2, and 3) are rare genetic disorders resulting in the overproduction of oxalate in the liver and that manifest in renal complications. This study sought to quantify the healthcare resource utilization (HCRU), costs, and clinical characteristics of PH patients. Authors Bernd Hoppe, Abigail Silber, Gavin Miyasato, Tom Koenig, Jeffrey Skaar, Craig Langman Journal American Society of Nephrology; ASN Kidney Week 2020 View publication…
This investigation assessed if the development of new-onset gout after KT was an independent risk factor for loss of graft function, as assessed by the need for maintenance hemodialysis following KT. Authors J. Li, D. Yin, M. Brigham, B. Lamoreaux, J. Kent, M. Francis-Sedlak, R. Johnson, N. Hadker, K. Francis, H. Sanchez, G. Miyasato Journal EULAR 2020 View publication…
Familial chylomicronemia syndrome (FCS) is a rare autosomal recessive disorder characterized by persistent extreme hypertriglyceridemia as a result of lipoprotein lipase deficiency. Canada is an important region for FCS research due to the high prevalence rates. The burden of illness and quality of life of Canadian patients, however, have been inadequately addressed in the literature. The objective of this study is to understand the burden of illness of FCS on Canadian patients’ lives. Authors Daniel Gaudet, Michael Stevenson, Nelly Komari,…
Hypoactive sexual desire disorder (HSDD) in women has been viewed inaccurately by some in the medical and payer community as analogous to erectile dysfunction (ED) in men. This literature review aims to highlight the distinctions between HSDD and ED. Authors Sheryl Kingsberg, Shruti Nambiar, Swagata Karkare, Nandini Hadker, Michelle Lim-Watson, Laura Williams, Julie Krop Journal National Library of Medicine; Current Medical Research & Opinion; June 2020 View publication…
This retrospective patient medical chart study aimed to assess the treatment patterns and real-world practice outcomes of NMIBC patients who were treated with BCG. Authors Sam Chang, Kyle Martin, Dan Shaffer, Amy Guo, Nandini Hadker Journal ISPOR Meeting; May 2020 View publication…
This analysis of real-world hospital data aimed to characterize the treatment regimens for inpatients experiencing rCDI, including both hospital- and community-acquired recurrence, and to compare these regimens to current treatment guidelines. Authors Gavin Miyasato, Hannah Li, Dushyant Katariya, Kevin Francis, Nandini Hadker Journal ISPOR Meeting; May 2020 View publication…
Network meta-analysis (NMA) compares multiple health technologies when there is a lack of direct evidence with randomized controlled trials (RCT) alone. While supplementing RCTs with robust real-world evidence (RWE) in NMAs has become standard practice, NMAs of RWE alone are now being used to gain insights into the patient experience in clinical practice. This SLR aimed to assess the quality of published RWE-only NMAs and evaluate the statistical methods used to account for clinical and statistical heterogeneity. Authors Nambiar S,…
This study analyzed direct medical costs of PWS patients and compared these to non-PWS patients; cost variation between those receiving growth hormone (GH) and those not was also evaluated. Authors Justin Li, David Yin, Qian Meng, Abigail Silber, Sina Aghsaei, Kevin Francis, Nandini Hadker, Theresa Strong, Jennifer Miller, Merlin Butler, Ann Manzardo, Michael Yeh, Shawn Czado Journal ISPOR Meeting; May 2020 View publication…
The purpose of this systematic literature review (SLR) was to assess current data on burden of survival for pediatric CXTpatients receiving platinum-based regimens in terms of hearing loss, specifically related to costs and quality of life (QoL)-based metrics. Authors Hennegan K, Silber A, Yuan A, Miyasato G, Li J, Soneji Y, Danker W Journal ISPOR Meeting; May 2020 View publication…
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