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The “Molecular Optimizer” Archetype: A Strategy for First-Launch Companies to Streamline Their Path to Market

The “molecular optimizer” archetype is a strategy utilized by first-launch companies to optimize existing molecules when developing their first product. Companies using this approach tend to be small and emerging biotech firms that are seeking a foothold to enter the market. The primary benefit of this approach is that the method offers a higher probability of regulatory approval and streamlines the manufacturer’s path to commercialization. With these benefits come some challenges related to access and pricing of a new product…

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Webinars

Picking Winners: Portfolio Management for a New Era

Available On Demand

Did you know 62% of products launched between September 2019 and December 2021 underperformed expectations in the first year of launch? What is going wrong, and how can we get it right? Join Trinity Life Sciences for a thought-provoking webinar to dive into the first white paper in our Industry Impact Series, Picking Winners: Portfolio Management for a New Era. Hear from Trinity’s Leslie Orne, President & CEO, Herman Sanchez, Chief Business Officer and Chad Faulkner, Partner, as they explore the challenges…

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White Papers

Picking Winners: Portfolio Management for a New Era

The biopharmaceutical industry is known for its promise of life-changing innovations, but many companies continue to advance the wrong therapies into the clinic, resulting in underperformance and wasted resources. This white paper explores the concentration of activity on well-trodden ground, and the lack of focus on true innovation. With increasing global pricing pressures and policy changes, it is more important than ever to be selective about the drugs that are advanced into the market. This white paper offers insights and…

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White Papers

Trinity Annual Drug Index

This report, the sixth in our Trinity Drug Index series, outlines key themes and emerging trends in the industry as we progress towards a new world of targeted and innovative products. We provide a comprehensive evaluation of the commercial performance over three years of novel drugs approved by the FDA in 2020, with commercial, therapeutic value and R&D investment scores for each. 2020 saw 58 unique drug and biologic approvals, of which the majority were Oncology (29%) followed by Neurology…

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White Papers

2023 Trinity Annual Drug Index

This report, the fifth in our Trinity Drug Index series, outlines key themes and emerging trends in the industry as we progress towards a new world of targeted and innovative products. We provide a comprehensive evaluation of the performance of novel drugs approved by the FDA in 2019, scoring each on its commercial performance, therapeutic value, and R&D investment. 2019 saw 53 unique drug and biologic approvals, of which the majority were neurology (~23%) followed by oncology (~21%). In this…

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Webinars

Business Development: Getting Pricing & Access Inputs Right

Available On Demand

Trinity invites life sciences executives to join us for a dynamic discussion on the most common high-impact challenges inherent in Business Development: What contributes to inaccurate pricing and market access assumptions in the quick-paced Business Development process? How do you de-risk pricing and access at each stage of the diligence process? Chad Faulkner, Partner in Trinity’s Strategic Advisory practice, will host this session and moderate a panel with special guests Monica Martin De Bustamante—Senior Partner & Head of Evidence, Value,…

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Webinars

Valuing an Early-Stage Asset in Pharma and Biotech: Innovative Approaches for Novel Therapies

Available On Demand

Secure success in bringing your novel therapies to market with Trinity’s innovative, holistic approach to valuing early-stage assets. Biopharma companies have been experiencing record levels of growth in recent years through M&A, co-developments, joint ventures, licensing agreements and other partnership deals. It is unlikely that this accelerated growth would have been sustained using traditional methodologies that are less able to generate realistic valuations for complex innovative therapies. Using traditional valuation methods, we likely would not have seen the commercialization of…

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White Papers

Smarter Commercialization Investment for First Launch Biopharma

With more momentum than ever to bring innovative medicines to market, there is increased pressure on emerging companies to get the launch right. The industry has seen record-breaking funding for therapies in recent years, and many have been commercialized by emerging biopharma companies launching for the first time. For many of these emerging biopharma companies, optimizing commercial launch spend is a critical consideration pre- and post-launch, and with limited funds it can be easy to misjudge the timing of key…

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White Papers

Valuing an Early-Stage Asset in Pharma and Biotech

In 2018, Trinity Life Sciences published a white paper titled, How to Approach Asset Valuation in Pharma & Biotech: Putting a price tag on emerging therapies. At the time, pharma and biotech firms were seeing venture investment growth of ~20% per year. This trend has only accelerated alongside the value of co-developments, partnerships, joint ventures, licensing agreements and other deals nearly doubling from 2019 to 2020. Quantifying the value of underlying assets throughout the clinical development process remains vital to…

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Webinars

Make Rapid Decisions with Confidence: Trinity’s Approach to Business Development Assessments

Available On Demand

Life science companies are often faced with situations that require quick decisions—from triage and/or pre-diligence phases through full due diligence. Trinity’s expert team routinely provides time-sensitive business development support, delivering robust insights and evidence-based answers in days. Come join us for a dynamic discussion on evaluating Business Development opportunities in life sciences. Key Webinar Topics What are the best approaches, data and tools to meet your business needs within your time horizon? How can you leverage rapid access to Real-World…

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