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Webinars

Unlock the Potential of Generative AI in Life Sciences Insights and Operations

May 2, 2024 | 1:00 - 1:45 PM ET

Generative AI (GenAI) has created an opportunity to re-think and significantly improve how we work. GenAI has the potential to make pharma professionals far more effective and valuable to their organizations. Join us for “Making AI Real,” a webinar series dedicated to exploring how to leverage generative AI across different areas within pharmaceutical commercial operations and medical affairs.

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Scientific Publications

Cost of Care Analysis for U.S. Patients with Prader-Willi Syndrome (PWS)

This study analyzed direct medical costs of PWS patients and compared these to non-PWS patients; cost variation between those receiving growth hormone (GH) and those not was also evaluated. Authors Justin Li, David Yin, Qian Meng, Abigail Silber, Sina Aghsaei, Kevin Francis, Nandini Hadker, Theresa Strong, Jennifer Miller, Merlin Butler, Ann Manzardo, Michael Yeh, Shawn Czado Journal ISPOR Meeting; May 2020 View publication…

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Scientific Publications

Comparison of Cesarean Section and Hysterectomy Outcomes Between Topical Powered Hemostat Cohorts: A Retrospective Analysis

The purpose of this systematic literature review (SLR) was to assess current data on burden of survival for pediatric CXTpatients receiving platinum-based regimens in terms of hearing loss, specifically related to costs and quality of life (QoL)-based metrics. Authors Hennegan K, Silber A, Yuan A, Miyasato G, Li J, Soneji Y, Danker W Journal ISPOR Meeting; May 2020 View publication…

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Scientific Publications

Evaluating the Burden of Survival of Platinum-induced Hearing Loss in Pediatric Solid Tumor Patients: A Systematic Literature Review

The purpose of this systematic literature review (SLR) was to assess current data on burden of survival for pediatric CXTpatients receiving platinum-based regimens in terms of hearing loss, specifically related to costs and quality of life (QoL)-based metrics. Authors Kalin Hennegan, Abigail Silber, Sumudu Dehipawala, Kevin Chithran, Donna Lockhart Journal ISPOR Meeting; May 2020 View publication…

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Scientific Publications

Epidemiology and Real-World Treatment of Chronic Graft-Versus-Host Disease Post Allogeneic Hematopoietic Cell Transplantation: A US Claims Analysis

Chronic Graft-Versus-Host Disease (cGVHD) is a complication of hematopoietic cell transplantation (HCT). While the clinical outcomes of cGVHD are well documented, few studies have assessed its treatment practices in the real-world. The objectives of this study are to quantify the prevalence of cGVHD, to examine provider prescribing patterns, and to evaluate the healthcare cost and resource utilization (HCRU) in a real-world US cGVHD population. Authors Carlos Bachier, Sanjay Aggarwal, Kalin Hennegan, Andrew Milgroom, Kevin Francis, Marcello Rotta Journal Blood; American…

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Scientific Publications

Healthcare Utilization Patterns Among Commercially Insured Patients with Prader-Willi Syndrome: A Retrospective Analysis of Administrative Claims

Prader-Willi syndrome (PWS) is a complex orphan endocrine disease characterized by hyperphagia and abnormal food-related behaviors that contribute to severe morbidity and early mortality along with a significant burden on patients and caregivers. Life-long medical care is required but the consistency of services rendered to this population has not been evaluated. This study characterized use of US hospital care, specialty physician care, and growth hormone (GH) therapy for PWS patients at different life stages. Authors Merlin Butler, Ann Manzardo, Theresa…

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Scientific Publications

U.S. Prevalence & Mortality of Prader-Willi Syndrome: A Population-Based Study of Medical Claims

Prader-Willi syndrome (PWS) is a complex developmental genetic disorder associated with hypotonia, poor feeding in neonates, onset of hyperphagia in early childhood, and shorter overall life expectancy. Prior epidemiology studies of PWS have examined smaller populations, with limited research in a US population. The aim of this study was to provide a contemporary estimate of PWS prevalence and annual all-cause mortality in the US using a large administrative medical claims dataset. Authors Shawn McCandless, Marissa Suh, David Yin, Michael Yeh,…

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Scientific Publications

Comparative Comorbidity Burden Among Patients with Prader-Willi Syndrome: A Population-Level Cohort Survey

Prader-Willi syndrome (PWS) is a rare, complex multi-system genetic disorder characterized by hyperphagia and abnormal food-related behaviors that contribute to severe morbidity and early mortality and to a significant burden on patients and caregivers. The hyperphagia seen in people with PWS can result in significant obesity. This study assessed rates of comorbidities associated with obesity, including type II diabetes (T2D), cardiovascular disease (CVD), and sleep apnea (SA) in a large US PWS vs. a non-PWS cohort. Authors Diane Stafford, Justin…

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Scientific Publications

Hypophosphatemia Associated with Intravenous Iron Therapies for Iron Deficiency Anemia

The purpose of this study was to systematically assess the prevalence, clinical consequences, and reporting of treatment-emergent hypophosphatemia within literature investigating IVI therapies marketed in the United States (US) Authors John Glaspy, Michelle Lim-Watson, Michael A Libre, Swagata Karkare, Nandini Hadker, Aleksandra Bajic-Lucas, William Strauss, Naomi Dahl Journal Therapeutics and Clinical Risk Management View publication…

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Scientific Publications

Evaluating the Ergonomic Outcomes of Digitally Assisted Vitreo-Retinal Surgery: A Systematic Literature Review

Recent developments in digitally assisted vitreo-retinal surgery (DAVS) and heads-up setup were introduced to the global ophthalmic surgical community to enhance visualization with digital signal amplification, higher resolution, and increased depth of field, while addressing some of the ergonomic challenges associated with conventional microscopes Authors Leighton Morris, William Wiley, Van Sandwick, Chiraag Lathia, Hang Cheng, Dina Abulon, Nandini Hadker, Kalin Hennegan Journal ISPOR EU 2020 View publication…

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Scientific Publications

Evaluating the Level of Endo-illumination Required during Digitally Assisted Vitreo-Retinal Surgery (DAVS): A Systematic Literature Review

While technological or procedural advances have resulted in low complication and re-operation rates, there are limitations of existing technologies — including but not limited to: surgical endo-illumination challenges, need for in-procedure adjustments, and additional information/support provided by other surgical devices — all of which can create challenges for surgeons during procedures Authors Leighton Morris, Alan Franklin, Van Sandwick, Chiraag Lathia, Hang Cheng, Nandini Hadker, Kalin Hennegan Journal ISPOR EU 2020 View publication…

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