Trinity Publishes Article in Applied Clinical Trials

Principal Jillian Scaife and Consultant Nick Simmons-Stern have authored an article recently published in Applied Clinical Trials titled: Designing Alzheimer’s Disease Clinical Trials For Success.  With an aging population, no current cure, and great costs of care, Alzheimer’s disease continues to pose significant public health concerns.  Recent estimates suggest that 28 million Americans will develop the disease by 2050.  Pharmaceutical companies are investing millions of dollars into Alzheimer’s disease research, but without careful clinical trial design, even the most promising drugs can fail.    This article reviews core considerations of two critical components of Alzheimer’s trial design – sample enrichment and outcomes selection.   Specifically, the article examines the role of diagnostic imaging and innovative cognitive and functional measures in cultivating successful Alzheimer’s disease treatments. Jillian Scaife is a graduate of Princeton University, where she received her degree in Molecular Biology.  Jillian received her MPH degree from the Johns Hopkins Bloomberg School of Public Health.  She received an MBA from the F. W. Olin Graduate School of Business at Babson College.  Nick graduated cum laude from Yale University, where he earned a BA with honors in Cognitive Science. Click here to read the full article.

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