Home / Intelligence / Scientific Publications / Comparative Comorbidity Burden Among Patients with Prader-Willi Syndrome: A Population-Level Cohort Survey
Prader-Willi syndrome (PWS) is a rare, complex multi-system genetic disorder characterized by hyperphagia and abnormal food-related behaviors that contribute to severe morbidity and early mortality and to a significant burden on patients and caregivers. The hyperphagia seen in people with PWS can result in significant obesity. This study assessed rates of comorbidities associated with obesity, including type II diabetes (T2D), cardiovascular disease (CVD), and sleep apnea (SA) in a large US PWS vs. a non-PWS cohort.
Authors
Diane Stafford, Justin Li, David Yin, Michael Yeh, Shawn Czado, Sina Aghsaei, Marissa Suh, Kevin Francis, Shawn McCandless
Journal
Journal of the Endocrine Society; Volume 4; Issue Supplement_1; April-May 2020
Related Intelligence
Case Studies
Dynamic Targeting Solution
Client Situation A large biopharma customer wanted to develop a dynamic targeting solution for HCPs in a particular market Trinity’s Role Project Outcomes *Based on model F1-score
Read More
Case Studies
NBA Insights Solution
As part of an enterprise-wide Digital Transformation initiative, our client was looking to optimize effectiveness of marketing execution channels—and maximize clinical and commercial outcomes—by personalizing campaigns through engaging HCPs with the most relevant content (safety, efficacy, support, etc.)
Read More
Blog
Rise with the waves: Italy – AIFA restructuring and budget reforms – Stepping into a new (uncertain) future?
Executive Summary The Italian Medicines Agency (AIFA) underwent transformative changes on January 30, 2024, following a much-anticipated reorganization. AIFA’s restructuring has already faced challenges, with the recent resignation of the newly created Scientific and Economic Commission’s (CSE) chairman followed by the appointment of a new acting chairman, highlighting the need for a stable and collaborative […]
Read More