Comparative Comorbidity Burden Among Patients with Prader-Willi Syndrome: A Population-Level Cohort Survey

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Prader-Willi syndrome (PWS) is a rare, complex multi-system genetic disorder characterized by hyperphagia and abnormal food-related behaviors that contribute to severe morbidity and early mortality and to a significant burden on patients and caregivers. The hyperphagia seen in people with PWS can result in significant obesity. This study assessed rates of comorbidities associated with obesity, including type II diabetes (T2D), cardiovascular disease (CVD), and sleep apnea (SA) in a large US PWS vs. a non-PWS cohort.


Authors

Diane Stafford, Justin Li, David Yin, Michael Yeh, Shawn Czado, Sina Aghsaei, Marissa Suh, Kevin Francis, Shawn McCandless

Journal

Journal of the Endocrine Society; Volume 4; Issue Supplement_1; April-May 2020

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