Home / Intelligence / Scientific Publications / U.S. Prevalence & Mortality of Prader-Willi Syndrome: A Population-Based Study of Medical Claims
Prader-Willi syndrome (PWS) is a complex developmental genetic disorder associated with hypotonia, poor feeding in neonates, onset of hyperphagia in early childhood, and shorter overall life expectancy. Prior epidemiology studies of PWS have examined smaller populations, with limited research in a US population. The aim of this study was to provide a contemporary estimate of PWS prevalence and annual all-cause mortality in the US using a large administrative medical claims dataset.
Authors
Shawn McCandless, Marissa Suh, David Yin, Michael Yeh, Shawn Czado, Sina Aghsaei, Justin Li, Kevin Francis, Nandini Hadker, Diane Stafford
Journal
Journal of the Endocrine Society; Volume 4; Issue Supplement_1; April-May 2020
Related Intelligence
Blog
2025 Oncology Mid-Year Check-in: Reflections & Expectations
Reflecting on the first half of 2025 including data from AACR, ASCO and EHA, we see several notable trends continuing to shape the oncology landscape. While development follows momentum observed the last few years, these learnings provide a clearer understanding into the next wave of innovation. Immunotherapy Moves Earlier in the Journey One of the […]
Read More
Case Studies
Optimizing HCP Call Planning with a Best‑in‑Class AIML Engine
The Situation Mid-Size Pharma, High-Potential HCP Identification Trinity’s Solution A digitally-integrated, AI-enabled ecosystem powering rep effectiveness and personalized HCP engagement Trinity AI assessed the client’s technology ecosystem and existing targeting engine to scope the context and needs for a more efficient solution. Trinity redesigned an AI-driven call plan engine to identify high-potential HCP targets in […]
Read More
Blog
Joint Clinical Assessment in the EU: What Life Sciences Companies Need to Know
March 2025 marked a pivotal moment for pharmaceutical and biotech companies operating in the European Union (EU) as the first two molecules began to proceed through the Joint Clinical Assessment (JCA) process. At a recent seminar hosted by Trinity Life Sciences, stakeholders gathered to explore the implications of this new regulatory framework and how to […]
Read More