U.S. Prevalence & Mortality of Prader-Willi Syndrome: A Population-Based Study of Medical Claims

Home / Intelligence / Scientific Publications / U.S. Prevalence & Mortality of Prader-Willi Syndrome: A Population-Based Study of Medical Claims

Prader-Willi syndrome (PWS) is a complex developmental genetic disorder associated with hypotonia, poor feeding in neonates, onset of hyperphagia in early childhood, and shorter overall life expectancy. Prior epidemiology studies of PWS have examined smaller populations, with limited research in a US population. The aim of this study was to provide a contemporary estimate of PWS prevalence and annual all-cause mortality in the US using a large administrative medical claims dataset.


Authors

Shawn McCandless, Marissa Suh, David Yin, Michael Yeh, Shawn Czado, Sina Aghsaei, Justin Li, Kevin Francis, Nandini Hadker, Diane Stafford

Journal

Journal of the Endocrine Society; Volume 4; Issue Supplement_1; April-May 2020

Related Intelligence

Webinars

Part D in Peril: The Inconvenient Math of IRA Part D Redesign 

August 14, 2025 | 12:00 – 12:45 PM ET

Medicare Part D is undergoing its most significant transformation in decades largely driven by the IRA. What does this mean for pharmaceutical manufacturers? Join us for an engaging discussion with Max Hunt, Partner at Trinity, and special guest Dan Simenc, clinical and actuarial expert at Milliman, as they provide perspectives on recent developments and future expectations for Medicare Part D and Medicare Advantage.

 Sign Up Now

Blog

NRDL 2024: Rare Diseases Deep Dive

China’s pharmaceutical landscape is not only vast in scale but also rapidly evolving with an emphasis on balancing access with affordability. This year’s NRDL update stands out. The introduction of the value rating system continues to raise the bar for clinical innovation, rewarding innovation that truly addresses unmet needs and demonstrates clear differentiation.  The National […]

 Read More

Webinars

AI-Powered HCP Call Planning: A Case Study in Business Transformation

July 23, 2025 | 12:00 – 12:45 PM ET

Field sales teams are a vital link between life sciences companies and healthcare professionals (HCPs), with effective call planning critical for success. As companies embrace new technologies to enhance their selling processes, they often face challenges such as resistance to change, training needs and integrating systems with existing workflows.  Join our panel discussion with Bausch […]

 Sign Up Now