As the year began, we couldn’t have foreseen the unprecedented impact the COVID-19 pandemic would have on US and Global enterprises. By mid-March, we were in lock-down, and priorities for Commercial and Medical Affairs organizations in the life sciences industry shifted. Leaders were working feverishly to enable virtual and digital channels to engage with customers as well as internal teams. Companies reached out to TGaS Advisors for our guidance in navigating this uncharted territory, and we stepped up to proactively support more than 1,800 individuals across 300 partner companies. The findings in this Advisory Brief are based on our work with these companies and, in particular, from key themes that emerged during our 2020 Fall Virtual Client Summit.